Successful Management of Multi-Drug Resistant TB in Pregnancy: A Case Report
E. C. Iwuoha *
Department of Community Medicine Abia State University Teaching Hospital, Aba, Nigeria.
E. O. Ezirim
Department of Obstetrics and Gynaecology Abia State University Teaching Hospital Aba, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Multi-drug resistant Tuberculosis (MDRTB) affects persons of all ages including women of child bearing age. The management of Multidrug resistant TB in pregnancy is controversial. However current guidelines for programmatic management of MDRTB include commencing pregnant women on treatment after the first trimester. Possible side effects of the drugs especially teratogenicity has been the major concern on whether or not to commence pregnant mothers.
We present a case of a 35 years old multi-gravida Nigerian woman who was managed for MDRTB during pregnancy. The patient was a previously drug sensitive TB patient who was treated for TB but lost to follow-up. At presentation pregnancy which was singleton was estimated at 19 weeks by Abdominal Ultra sound scan. Patient was treated with second line anti-Tb drugs and delivered at 38 weeks gestation; a healthy female baby with a birth weight of 2.5 kg.
Conclusions: Pregnant MDRTB patients can have successful outcomes if commenced on treatment after first trimester.
Keywords: Pregnancy, multi-drug resistant TB, second line drugs