Prevalence of Malaria Infection among HIV Infected Pregnant Women Receiving Care at Public Health Facilities in Ondo State of Nigeria

Main Article Content

T. A. Olusi
M. B. Adediran
M. O. Oniya

Abstract

Malaria and HIV are important challenging infections in Nigeria. Co-infections of this duo in pregnancy has been associated with various adverse pregnancy outcomes including anaemia, low birth weight, premature birth, maternal and neonatal death. This study was carried out to determine the prevalence of malaria infection among HIV infected pregnant mothers reporting for routine antenatal checkup in two major state owned hospitals in Ondo city. The cross-sectional study conducted between May and September 2018 had 93 HIV infected pregnant women as participants. The overall prevalence rate of malaria was 52.6% and the highest rate was recorded among separated/divorced participants (83.3%). Malaria infection was found to be statistically significant in relative to CD4+ cell counts where malaria infection prevalence ranges from 22.2% to 71.4% ( χ2 =9.22, P=0.03). This study has found that the prevalence of malaria was high among HIV infected pregnant women in Ondo city and that factors such as gravidity, reported fever and residence do not vary significantly on the univariate analysis employed in this study.

Keywords:
Malaria, HIV, prevalence, pregnant women, Ondo city.

Article Details

How to Cite
Olusi, T. A., Adediran, M. B., & Oniya, M. O. (2019). Prevalence of Malaria Infection among HIV Infected Pregnant Women Receiving Care at Public Health Facilities in Ondo State of Nigeria. Asian Journal of Pregnancy and Childbirth, 2(3), 1-7. Retrieved from http://www.journalajpcb.com/index.php/AJPCB/article/view/30101
Section
Original Research Article

References

Hochman S, Kim K. The Impact of HIV and malaria coinfection: What is known and suggested venues for further study. Interdisciplinary Perspectives on Infectious Diseases. 2009;1–8.
Available:https://doi.org/10.1155/2009/617954

Tay SCK, Badu K, Mensah AA, Gbedema SY. The prevalence of malaria among HIV seropositive individuals and the impact of the co-infection on their hemoglobin levels. Annals of Clinical Microbiology and Antimicrobials. 2015;14(1):4-11.
Available:https://doi.org/10.1186/s12941-0150064-6

Mockenhaupt FP, Bedu-addo G, Junge C, Hommerich L, Eggelte TA, Bienzle U, Maji AK. History of antimalarials background antimalarials. Malaria Journal. 2015; 3(1):1–8. Available:https://doi.org/10.3909/riog0091

Newman RD, Robalo M, Quakyi I. Malaria during pregnancy: Epidemiology, current prevention strategies, and future directions. Emerging Infectious Diseases. 2004;10(11):e21. DOI:10.3201/eid1011.040624_09

Chou R, Cantor A, Bougatsos C, Zakher B. Screening for HIV in pregnant women: Systematic review to update the U.S. Preventive Services Task Force Recommendation. Rockville (MD): Agency for Healthcare Research and Quality (US); 2012.
Available:http://www.ncbi.nlm.nih.gov/books/NBK114880/

UNAIDS. Joint United Nations Programme on HIV/AIDS, Global HIV/AIDs statistics- fact sheet; 2019.

Kendall T, Danel I. Research and evaluation agenda for HIV and maternal health in sub-Saharan Africa: women and health initiative working paper No. 1. Women and Health Initiative, Harvard School of Public Health: Boston, MA; 2014. Available: http://www.mhtf.org

Ter Kuile FO, Parise ME, Verhoeff FH. The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-Saharan Africa. TheAmerican Journal of Tropical Medicine and Hygiene. 2004;71(2);41–54.

Karp CL, Auwaerter PG. Coinfections with HIV and tropical infectious diseases. II. Helminthic, fungal, bacterial and viral pathogens. Journal of Clinical Infectious Diseases. 2007;45(9):1214-1220.

Chaisson RE, Moore RD. Prevention of opportunistic infections in the era of improved antiretroviral therapy. Journal of Immune Deficiency Syndrome Human Retrovirol. 1997;16(1):14-22.

Bawa GH. Audit on the management of virtual transmission of HIV/AIDS. Presented in a joint obstetric and pediatric meeting Deter Borough district hospital United Kingdom; 2005.

UNAIDS. Joint United Nations Programme on HIV/AIDS, Global HIV/AIDs statistics- fact sheet; 2016.

Ako-Nai AK, Ebhodaghe BI, Osho PO, Adejuyigbe EA, Adefemi FM, Ikuomola AA, Kassim OO. The epidemiology of HIV seropositive malaria infected pregnant women in Akure metropolis, Southwestern, Nigeria. Annals of Tropical Medcine and Public Health. 2013;6(5):519-525.

Olusi TA, Abe AF. Co-infection of HIV and malaria parasites in pregnant women attending major ante-natal health facilities in Akure, Ondo State, Nigeria. Journal of Parasitology and Vector Biology. 2014; 6(9):124-130.

Dada E. Prevalence of malaria and co-infection with Human Immuno-Deficiency Virus (HIV) in selected areas of Ondo State, Nigeria. International Journal of Tropical Disease & Health. 2015;8(1):34–39. Available:https://doi.org/10.9734/ijtdh/2015/16987

Houmsou RS, Hile TD, Wama BE, Bingbeng JB. Elkanah SO, Kela SL, Garba LC, Amuta EU. Malria infection in HIV infected pregnant women attending a rural antenatal clinic in Nigeria. Hindawi Publishing Corporation Advances in Epidemiology. 2014;694213:6.

WHO. Microscopy for the detection, identification and quantification of malaria parasite on thick and thin films. Research Malaria Microscopy Standard Working Group. Geneva: Switzerland; 2015.

Asmamaw T, Alemu A, Alemu A, Unakal C. Prevalence of malaria and HIV among pregnant women attending antenatal clinics at Felege Hiwot Referral Hospital and Addis Zemen Health Center in northwest of Ethiopia. International Journal of Life Sciences Biotechnology and Pharma Research. 2013;2(3):81–91.

Elliott SR, Brennan AK, Beeson JG, Tadesse E, Molyneux ME, Brown GV, Rogerson SJ. Placental malaria induces variant-specific antibodies of the cytophilic subtypes immunoglobulin G1 (IgG1) and IgG3 that correlate with adhesion inhibitory activity. Journal of American Society for Microbiology Infection and Immunity. 2005;73:5903-5907.
DOI: 10.1128/IAI.73.9.5903-5907.2005

Wumba RD, Zanga J, Aloni MN, Mbanzulu K, Kahindo A, Mandina MN, Ekila MB, Ekila MB, Mouri O, Kendjo E. Interactions between malaria and HIV infections in pregnant women: A first report of the magnitude, clinical and laboratory features, and predictive factors in kinshasa, the Democratic Republic of Congo. Malaria Journal. 2015;14:82.

Okiro EA, Snow RW. The relationship between reported fever and Plasmodium falciparum infection in African children. Malaria Journal. 2010;9:99.